Drosophila CAP-D2 is required for condensin complex stability and resolution of sister chromatids.

@article{Savvidou2005DrosophilaCI,
  title={Drosophila CAP-D2 is required for condensin complex stability and resolution of sister chromatids.},
  author={Ellada Savvidou and Neville Cobbe and S. Steffensen and Sue Cotterill and M. Heck},
  journal={Journal of cell science},
  year={2005},
  volume={118 Pt 11},
  pages={2529-43}
}
The precise mechanism of chromosome condensation and decondensation remains a mystery, despite progress over the last 20 years aimed at identifying components essential to the mitotic compaction of the genome. In this study, we analyse the localization and role of the CAP-D2 non-SMC condensin subunit and its effect on the stability of the condensin complex. We demonstrate that a condensin complex exists in Drosophila embryos, containing CAP-D2, the anticipated SMC2 and SMC4 proteins, the CAP-H… CONTINUE READING

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