Drop-the-losers design: normal case.

@article{Sampson2005DropthelosersDN,
  title={Drop-the-losers design: normal case.},
  author={Allan R. Sampson and Michael W. Sill},
  journal={Biometrical journal. Biometrische Zeitschrift},
  year={2005},
  volume={47 3},
  pages={257-68; discussion 269-81}
}
Drop-the-losers designs are statistical designs which have two stages of a trial separated by a data based decision. In the first stage k experimental treatments and a control are administered. During a transition period, the empirically best experimental treatment is selected for continuation into the second phase, along with the control. At the study's end, inference focuses on the comparison of the selected treatment with the control using both stages' data. Traditional methods used to make… CONTINUE READING

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