Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter.

@article{Singh2007DronedaroneFM,
  title={Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter.},
  author={Bramah N. Singh and Stuart J. Connolly and Harry J. G. M. Crijns and Denis Roy and Peter Russell Kowey and Alessandro Capucci and David Radzik and Etienne M. Aliot and Stefan H. Hohnloser},
  journal={The New England journal of medicine},
  year={2007},
  volume={357 10},
  pages={987-99}
}
BACKGROUND Amiodarone is effective in maintaining sinus rhythm in atrial fibrillation but is associated with potentially serious toxic effects. Dronedarone is a new antiarrhythmic agent pharmacologically related to amiodarone but developed to reduce the risk of side effects. METHODS In two identical multicenter, double-blind, randomized trials, one conducted in Europe (ClinicalTrials.gov number, NCT00259428 [ClinicalTrials.gov] ) and one conducted in the United States, Canada, Australia… CONTINUE READING
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