Driving folliculogenesis by the oocyte-somatic cell dialog: Lessons from genetic models.

@article{Monniaux2016DrivingFB,
  title={Driving folliculogenesis by the oocyte-somatic cell dialog: Lessons from genetic models.},
  author={Danielle Monniaux},
  journal={Theriogenology},
  year={2016},
  volume={86 1},
  pages={41-53}
}
This review focuses on the role of the dialog between the oocyte and its companion somatic cells in driving folliculogenesis from the primordial to the preovulatory follicle stage. Mouse and sheep genetic models have brought complementary evidence of these cell interactions and their consequences for ovarian function. In mouse, the deletion of genes encoding connexins has shown that functional gap junction channels between oocytes and granulosa cells and between granulosa cells themselves… CONTINUE READING
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