Driven to Autoimmunity The Nod Mouse

  title={Driven to Autoimmunity The Nod Mouse},
  author={Alena M. Gallegos and Michael John Bevan},
In the lymphoid system, T cells respond to space or under-crowding by dividing to maintain their numbers. In this issue of Cell, evidence is provided that this homeostatic proliferation, coupled with excess production of a cytokine, IL-21, is a key factor in susceptibility to autoimmune diabetes. 
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