Dripping, Jetting, Drops and Wetting: the Magic of Microfluidics

  title={Dripping, Jetting, Drops and Wetting: the Magic of Microfluidics},
  author={Andrew S. Utada and Liang‐Yin Chu and Alberto Fern{\'a}ndez-Nieves and Darren R. Link and Christian Holtze and David A. Weitz},
  journal={Mrs Bulletin},
The following article is based on the Symposium X presentation given by David A. Weitz (Harvard University) on April 11, 2007, at the Materials Research Society Spring Meeting in San Francisco. The article describes how simple microfluidic devices can be used to control fluid flow and produce a variety of new materials. Based on the concepts of coaxial flow and hydrodynamically focused flow, used alone or in various combinations, the devices can produce precisely controlled double emulsions… 

Capillary-Based Microfluidics-Coflow, Flow-Focusing, Electro-Coflow, Drops, Jets, and Instabilities.

In this review, the current understanding of drop and jet formation in capillary-based microfluidic devices for two primary flow configurations, coflow and flow-focusing is summarized.

Droplet Manipulations in Two Phase Flow Microfluidics

This review summarizes the currently existing techniques for manipulating droplets in two-phase flow microfluidics, and very recent developments like the use of acoustic waves, magnetic fields, surface energy wells, and electrostatic traps and rails are discussed.

One-step formation of multiple emulsions in microfluidics.

A robust way to create multiple emulsions with controllable shell thicknesses that can vary over a wide range of fluids, by controlling the thickness of each layer of the jet.

Droplet Microreactors for Materials Synthesis

The miniaturization of fluid flow and analytical systems has created exciting avenues of scientific and engineering research in materials synthesis. The conventional microfluidic devices have

Robust coaxial capillary microfluidic device for the high throughput formation of polymersomes

AbstractA microfluidic device incorporating three coaxial capillaries set in a single block of ultra-high molecular weight polyethylene (UHMWPE) for the rapid formation of monodisperse double

Corrugated interfaces in multiphase core-annular flow

Microfluidic devices can be used to produce highly controlled and monodisperse double or multiple emulsions. The presence of inner drops inside a jet of the middle phase introduces deformations in

Engineering the surface properties of microfluidic stickers.

A simple and effective method to tailor the wetting and adhesion properties of thiolene-based microfluidic devices and provides the details of two complementary methods to achieve surface patterning.

Robust coaxial capillary microfluidic device for the high throughput formation of polymersomes

A microfluidic device incorporating three coaxial capillaries set in a single block of ultra-high molecular weight polyethylene (UHMWPE) for the rapid formation of monodisperse double emulsions and

SAW-driven droplet jetting technology in microfluidic: A review.

This article reviews and reorganizes SAW- microfluidic jetting technology from decades of years, referring to the interaction mechanism theory of SAW and fluid, experimental methods of Saw-microfluidics jetting, effects of related parameters on objected pinch-off droplets, and applications of individual structures.



Monodisperse Double Emulsions Generated from a Microcapillary Device

It is shown that the droplet size can be quantitatively predicted from the flow profiles of the fluids, which makes this a flexible and promising technique.

Formation of dispersions using “flow focusing” in microchannels

A flow-focusing geometry is integrated into a microfluidic device and used to study drop formation in liquid–liquid systems. A phase diagram illustrating the drop size as a function of flow rates and

Monodisperse Emulsion Generation via Drop Break Off in a Coflowing Stream

We describe an experimental technique for the production of highly monodisperse emulsions (with minimum achievable polydispersities <3%). The phase to be dispersed is introduced into a coflowing,

Perfectly monodisperse microbubbling by capillary flow focusing.

The physics of the phenomenon is described and closed expressions for the bubble diameter are obtained as a function of the liquid and gas properties, geometry, and flow parameters, from a large set of experimental results.

Microfluidics: Fluid physics at the nanoliter scale

Microfabricated integrated circuits revolutionized computation by vastly reducing the space, labor, and time required for calculations. Microfluidic systems hold similar promise for the large-scale

Generation of polymerosomes from double-emulsions.

A new method for generating polymer vesicles from double emulsions from the breakup of concentric fluid streams, which directs the self-assembly of the dissolved diblock copolymers into vesicular structures.

Dripping-jetting transitions in a dripping faucet.

New experiments and simulations show that high viscosity (micro) liquids, e.g., syrup, transition directly from simple dripping to jetting as Q increases, and values of Q for transition from dripping to jets are estimated from scaling arguments and shown to accord well with simulations.

Dewetting instability during the formation of polymersomes from block-copolymer-stabilized double emulsions.

It is described how the presence of excess polymer can induce a transition from complete wetting to partial wetting of the middle phase, resulting in polymer shells with inhomogeneous thicknesses.

Toward a Tetravalent Chemistry of Colloids

We propose coating spherical particles or droplets with anisotropic nanosized objects to allow micron-scale colloids to link or functionalize with a 4-fold valence, similar to the sp3 hybridized

Polymersomes: tough vesicles made from diblock copolymers.

The results suggest a new class of synthetic thin-shelled capsules based on block copolymer chemistry, and both the membrane bending and area expansion moduli of electroformed polymersomes (polymer-based liposomes) fell within the range of lipid membrane measurements.