Drinking drivers in Sweden who consume denatured alcohol preparations: an analytical-toxicological study.

@article{Jones1989DrinkingDI,
  title={Drinking drivers in Sweden who consume denatured alcohol preparations: an analytical-toxicological study.},
  author={A. Wayne Jones and M Lund and E K Margareta Andersson},
  journal={Journal of analytical toxicology},
  year={1989},
  volume={13 4},
  pages={
          199-203
        }
}
In the course of analyzing blood samples from drunk drivers, several low molecular weight volatiles were occasionally identified in addition to ethanol on the gas chromatograms. Among 21, 153 blood specimens analyzed during 1986, 77 contained ethanol as well as other volatile agents at the following mean concentrations: ethanol 2090 mg/L (range 830-3410), methanol 49.6 mg/L (range 20-178), acetone 88.3 mg/L (range 12-307), 2-propanol 32.2 mg/L (range 4-99), 2-butanone 49.2 mg/L (range 5-144… 
Interfering substances identified in the breath of drinking drivers with Intoxilyzer 5000S.
  • A. Jones
  • Medicine
    Journal of analytical toxicology
  • 1996
TLDR
Allegations of false high breath-alcohol readings obtained because of the presence of volatile organic compounds (VOCs) other than ethanol is a well-known defense argument in trials concerning driving under the influence of alcohol (DUI).
Two fatalities from ingestion of acetonitrile: limited specificity of analysis by headspace gas chromatography.
TLDR
A married couple was found dead in bed at their home, and the police investigation indicated that they might have ingested methanol and/or ethanol the previous evening, and acetonitrile was mistakenly identified as ethanol.
Assessment of response of the Intoxilyzer 8000C to volatiles of forensic relevance in vitro, part I: acetone, isopropanol, and methanol.
TLDR
The response of the Intoxilyzer 8000C (version approved for evidentiary breath alcohol testing in Canada) to volatile solvents in vitro is described and the potential for significant undetected BEC overestimation is low.
Determination of ethanol in breath for legal purposes using a five-filter infrared analyzer: studies on response to volatile interfering substances.
TLDR
It is confirmed that relatively few apprehended drivers in Sweden have elevated concentrations of VOCs in breath other than ethanol, and even the aborted breath tests, to a large extent, contained ethanol above the legal limit for driving.
Variability of the blood/breath alcohol ratio in drinking drivers.
TLDR
During 1992, 1993, and 1994, the mean blood/breath ratios of alcohol were remarkably constant, being 2409 +/- 288, 2407 +/- 206, and 2421 +/- 235, respectively, and the values were not significantly influenced by the person's age, gender, or blood-alcohol content.
Fatality from drinking denatured alcohol and hypothermia.
  • A. Jones
  • Medicine
    Journal of analytical toxicology
  • 2011
TLDR
The lower concentrations of ethanol, acetone, and isopropanol in postmortem blood compared with antemortem blood indicate the metabolism of these substances during the 21-h survival period when the patient received emergency hospital treatment.
Biotransformation of acetone to isopropanol observed in a motorist involved in a sobriety check.
TLDR
This case scenario provides a good example of severe metabolic ketoacidosis in an ostensibly healthy man driving on the highway.
Elimination half-life of acetone in humans: case reports and review of the literature.
  • A. Jones
  • Medicine
    Journal of analytical toxicology
  • 2000
TLDR
In a hospital patient who had ingested denatured alcohol, the elimination half-life (t(1/2))) of acetone during detoxification was 27 h and not 3-5 h as reported by other workers, and several other literature reports support the notion of a long eliminationHalf-life of 17-27 h for acetone compared with a t(1-3 h for isopropanol.
Comparison of blood-ethanol concentration in deaths attributed to acute alcohol poisoning and chronic alcoholism.
TLDR
Various explanations are offered for the differences in blood-ethanol and blood-acetone in acute poisoning and alcoholism deaths such as chronic tolerance, alcohol-related organ and tissue damage, positional asphyxia or suffocation by inhalation of vomit, exposure to cold coupled with alcohol-induced hypothermia, as well as various metabolic disturbances such as hypoglycemia and ketoacidosis.
Patterns of the most abundant volatiles detected in post-mortem blood
TLDR
The determination of the volatiles' concentrations in autopsy blood samples received from 483 routinely autopsied corpses and classification of their patterns according to the manner of death, and the presence of putrefaction were determined by a validated gas chromatographic method.
...
1
2
3
...

References

SHOWING 1-5 OF 5 REFERENCES
Computer-aided headspace gas chromatography applied to blood-alcohol analysis: importance of online process control.
TLDR
The reduced prosecution BAC is less than the actual BAC with a statistical confidence of 99.9% and is made to compensate for random and systematic errors inherent in the method.
Metabolism of acetone to isopropyl alcohol in rats and humans.
TLDR
High levels of blood acetone could result in transformation to isopropyl alcohol, according to this hypothesis, which was investigated in a study of normal and diabetic rats.
Alcoholics who drink mouthwash: the spectrum of nonbeverage alcohol use.
TLDR
The 48 NBA users reported surprisingly few toxic symptoms from acute ingestion, perhaps because tolerance to some substances in NBA may occur, and Isopropyl alcohol was the exception, reproducibly causing symptoms suggestive of severe gastritis.
The effect of biologic specimen type on the gas chromatographic headspace analysis of ethanol and other volatile compounds.
Gas chromatographic analyses of 37 degrees C headspace vapors above liquid phases saturated with sodium chloride demonstrated that the partitioning of isopropanol, n-propanol, and t-butanol from
Methanol in Normal Human Breath
Free methanol has been detected and measured, by gas-liquid chromatography, in the breath of several normal, healthy humans. It is suggested that this is a metabolic product rather than the result of