Dried blood spots, pharmacokinetic studies and better medicines for children.


Determining circulating drug concentrations in children is an ongoing obstacle to the development of age-appropriate dosing regimens. The requirement for small blood sample volumes in children compared with adults is a significant barrier to obtaining age-specific pharmacokinetic-pharmacodynamic data for this population and hence optimizing the efficacy and… (More)
DOI: 10.4155/BIO.11.19


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