Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle.

@article{Culligan2002DrasticRO,
  title={Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle.},
  author={Kevin G. Culligan and Niamh Banville and Paul J. Dowling and Kay Ohlendieck},
  journal={Journal of applied physiology},
  year={2002},
  volume={92 2},
  pages={435-45}
}
Although the reduction in dystrophin-associated glycoproteins is the primary pathophysiological consequence of the deficiency in dystrophin, little is known about the secondary abnormalities leading to x-linked muscular dystrophy. As abnormal Ca(2+) handling may be involved in myonecrosis, we investigated the fate of key Ca(2+) regulatory membrane proteins in dystrophic mdx skeletal muscle membranes. Whereas the expression of the ryanodine receptor, the dihydropyridine receptor, the Ca(2… CONTINUE READING

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Brain dystrophin-glycoprotein complex: persistent expression of -dystroglycan, impaired oligomerisation of Dp71 and up-regulation 443 CALSEQUESTRIN-LIKE PROTEINS

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Excitation-contraction-relaxation cycle: role of Ca2 -regula 444 CALSEQUESTRIN-LIKE PROTEINS

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