Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis

@article{Carlton2007DraftGS,
  title={Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis},
  author={Jane M. Carlton and Robert P. Hirt and Joana C. Silva and Arthur L. Delcher and Michael C. Schatz and Qi Zhao and Jennifer R. Wortman and Shelby L. Bidwell and U. Cecilia M. Alsmark and S{\'e}bastien Besteiro and Thomas Sicheritz-Pont{\'e}n and Christophe J Noel and Joel B. Dacks and Peter G. Foster and Cedric Simillion and Yves van de Peer and Diego Miranda-Saavedra and Geoffrey J. Barton and Gareth D Westrop and Sylke Müller and Daniele Dess{\`i} and Pier Luigi Fiori and Qinghu Ren and Ian T. Paulsen and Hanbang Zhang and Felix D Bastida-Corcuera and Augusto Simoes-Barbosa and Mark T Brown and Richard D. Hayes and Mandira Mukherjee and Cheryl Okumura and Rachel E Schneider and Alias J Smith and {\vS}těp{\'a}nka Vaň{\'a}{\vc}ov{\'a} and Maria Villalvazo and Brian J. Haas and Mihaela Pertea and Tamara V. Feldblyum and Terry R. Utterback and Chung-Li Shu and Kazutoyo Osoegawa and Pieter J de Jong and Ivan Hrdý and Lenka Horv{\'a}thov{\'a} and Zuzana Zub{\'a}{\vc}ov{\'a} and Pavel Dole{\vz}al and Shehre-Banoo Malik and John M. Logsdon and Katrin Henze and Arti Gupta and Ching C. Wang and Rebecca L Dunne and J. A. Upcroft and P. Upcroft and Owen White and Steven L. Salzberg and Petrus Tang and Cheng-Hsun Chiu and Ying-Shiung Lee and T Martin Embley and Graham H. Coombs and Jeremy C. Mottram and Jan Tachezy and Claire Fraser-Liggett and Patricia J. Johnson},
  journal={Science},
  year={2007},
  volume={315},
  pages={207 - 212}
}
We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the ∼160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion, in conjunction with the shaping of metabolic pathways that likely transpired through lateral gene transfer from bacteria, and amplification of specific gene families implicated in pathogenesis and phagocytosis of host proteins… 

Trichomonas vaginalis pathobiology new insights from the genome sequence.

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