Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis

Abstract

During the final stages of embryogenesis, the Drosophila embryo exhibits a dorsal hole covered by a simple epithelium of large cells termed the amnioserosa (AS). Dorsal closure is the process whereby this hole is closed through the coordination of cellular activities within both the AS and the epidermis. Genetic analysis has shown that signalling through… (More)
DOI: 10.1016/j.mod.2007.09.002

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