Dpc4 is expressed in virtually all primary and metastatic pancreatic endocrine carcinomas

@article{Scarpa2001Dpc4IE,
  title={Dpc4 is expressed in virtually all primary and metastatic pancreatic endocrine carcinomas},
  author={Aldo Scarpa and Simonetta Orlandini and Patrick S Moore and Nicholas R. Lemoine and Stefania Beghelli and Antonella Baron and Massimo Falconi and Giuseppe Zamboni},
  journal={Virchows Archiv},
  year={2001},
  volume={440},
  pages={155-159}
}
DPC4/Smad4 is inactivated in about 50% of pancreatic ductal cancers. It has been recently reported that this gene is also inactivated in neoplasms arising from pancreatic islet cells, a phenomenon suggested to be related to similar progressions of malignancy found in common ductal cancers. To evaluate this possibility, we analysed 20 metastases of… CONTINUE READING