Doxorubicin-mediated apoptosis in glioma cells requires NFAT3


Nuclear factor of activated T cells (NFAT), a family of transcription factors, has been implicated in many cellular processes, including some cancers. Here, we characterize, for the first time, the role of NFAT3 in doxorubicin (DOX)-mediated apoptosis, migration, and invasion in SNB19 and U87 glioma cells. This study demonstrates that the specific knockdown… (More)
DOI: 10.1007/s00018-009-0157-5


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