Doxorubicin-loaded biodegradable self-assembly zein nanoparticle and its anti-cancer effect: Preparation, in vitro evaluation, and cellular uptake.

@article{Dong2016DoxorubicinloadedBS,
  title={Doxorubicin-loaded biodegradable self-assembly zein nanoparticle and its anti-cancer effect: Preparation, in vitro evaluation, and cellular uptake.},
  author={Fangyuan Dong and Xiao-li Dong and L. Zhou and Huihui Xiao and Pui-Yu Ho and Man-Sau Wong and Yi Wang},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2016},
  volume={140},
  pages={324-331}
}
Cancer is one top leading cause of the deaths worldwide. Various anticancer drugs, which can effectively kill cancer cells, have been developed in the last decade. However, the problem is still about the low therapeutic index of the drugs, which means that the effective dose of drugs will cause cytotoxicity to normal cells. A strategy based on drug nano… CONTINUE READING