Doxorubicin , and Vinblastine Cytotoxicity by Dipyridamole Comparison of the Synergistic Potentiation of Etoposide , Updated

Dipyridamole (DPM) enhanced sensitivity to etoposide (VP-16), doxorubicin (DOX), and vinblastine (VBL) in a human ovarian carcinoma cell line that was already relatively sensitive to all three agents. This interaction was shown to be truly synergistic by median effect analysis over a 2 log cell kill. The combination index at 50% cell kill (CI»)»as used to… (More)