Doxepin effects on chronic pain, depression and plasma opioids.

  title={Doxepin effects on chronic pain, depression and plasma opioids.},
  author={Stuart R. Hameroff and Randall C. Cork and Kira Scherer and B R Crago and Charles P. Neuman and J R Womble and Thomas P. Davis},
  journal={The Journal of clinical psychiatry},
  volume={43 8 Pt 2},
Thirty patients with chronic low back or cervical pain combined with clinical depression were studied in a six-week, randomized, double-blind comparison of doxepin and placebo. Dependent variables included Hamilton Depression Scores, the Clinical Global Assessment Scale, and Profile of Mood States (POMS), and subjective ratings (visual analogue scales) of pain severity, percent of time pain felt, and effect of pain on activity, muscle tension, sleep, mood, and analgesic drug consumption. Plasma… CONTINUE READING
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