Downstream Targets of Lmo4 Are Modulated by Cisplatin in the Inner Ear of Wistar Rats

@inproceedings{Jamesdaniel2014DownstreamTO,
  title={Downstream Targets of Lmo4 Are Modulated by Cisplatin in the Inner Ear of Wistar Rats},
  author={Samson Jamesdaniel},
  booktitle={PloS one},
  year={2014}
}
Lmo4, a transcriptional regulator, appears to be a key player in mediating the cochlear pathology in cisplatin ototoxicity, as it controls cellular responses by modulating the formation of transcriptional complexes. We provided the first evidence of in vivo nitration of Lmo4 in cisplatin ototoxicity. Our data suggested that nitration of Lmo4 and associated… CONTINUE READING