Downregulation of the cAMP/PKA Pathway in PC12 Cells Overexpressing NCS-1


It is well known that dopamine imbalances are associated with many psychiatric disorders and that the dopaminergic receptor D2 is the main target of antipsychotics. Recently it was shown that levels of two proteins implicated in dopaminergic signaling, Neuronal calcium sensor-1 (NCS-1) and DARPP-32, are altered in the prefrontal cortex (PFC) of both… (More)
DOI: 10.1007/s10571-010-9562-4


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