Downregulation of miR-95-3p inhibits proliferation, and invasion promoting apoptosis of glioma cells by targeting CELF2.

@article{Fan2015DownregulationOM,
  title={Downregulation of miR-95-3p inhibits proliferation, and invasion promoting apoptosis of glioma cells by targeting CELF2.},
  author={Bo Fan and Bao-hua Jiao and Feng-Shi Fan and S Lu and Jian Fei Song and Cheng-Yong Guo and Jian-kai Yang and Liang Yang},
  journal={International journal of oncology},
  year={2015},
  volume={47 3},
  pages={1025-33}
}
Gliomas are the most common and aggressive types of tumors in human brain, of which the prognosis remains dismal because of their biological behavior. The involvement of miRNAs in tumorigenesis of various kinds of cancers drives us to explore new miRNAs related to gliomas. We measured expression level of miR‑95‑3p by qRT-PCR in human glioma and non-neoplasm brain tissues and found that higher level of miR‑95‑3p in glioma tissues of higher grade. Biological functions of miR‑95‑3p on glioma cells… CONTINUE READING

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