Downregulation of miR-205 in migrating epithelial tongue facilitates skin wound re-epithelialization by derepressing ITGA5.

@article{Wang2016DownregulationOM,
  title={Downregulation of miR-205 in migrating epithelial tongue facilitates skin wound re-epithelialization by derepressing ITGA5.},
  author={Tao Wang and Na Zhao and Shuang Long and Lan Ge and Aiping Wang and HuiQin Sun and Xinze Ran and Zhongmin Zou and Junping Wang and Yongping Su},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1862 8},
  pages={
          1443-52
        }
}
Keratinocyte migration is essential for re-epithelialization during skin wound healing, but the molecular mechanisms regulating this cellular response remain to be completely clarified. Here we show that keratinocyte-specific miR-205 is significantly downregulated in the leading edge of the migrating epithelial tongue after skin injury in mice. In HaCaT… CONTINUE READING