Downregulation of long non-coding RNA TRIM52-AS1 functions as a tumor suppressor in renal cell carcinoma.

@article{Liu2016DownregulationOL,
  title={Downregulation of long non-coding RNA TRIM52-AS1 functions as a tumor suppressor in renal cell carcinoma.},
  author={Zan Liu and Haiyan Yan and Shunyao Xia and Cheng Zhang and Youcheng Xiu},
  journal={Molecular medicine reports},
  year={2016},
  volume={13 4},
  pages={
          3206-12
        }
}
Long non-coding RNAs (lncRNAs) are important regulators of gene expression, interacting with the major pathways of cell growth, proliferation, differentiation and survival. Alterations in the function of lncRNAs promote tumor formation, progression and metastasis. The purpose of the present study was to identify novel tumor suppressor lncRNAs, and elucidate their physiological function and mechanism in renal cell carcinoma (RCC). The results of the present study revealed that the expression of… 
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