Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes.

Abstract

Normal human melanocytes have been shown to respond to the signal peptide endothelin by increased proliferation and melanin formation. Contradictory findings, however, have been reported about which of the two endothelin receptors (EDNRA or EDNRB) is expressed in normal melanocytes and melanoma cells. Moreover it was not clear whether malignant cells differ… (More)

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Cite this paper

@article{Eberle1999DownregulationOE, title={Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes.}, author={J{\"u}rgen Eberle and Sandra Weitmann and Oliver Thieck and Herbe Pech and M. Paul and Constanin E Orfanos}, journal={The Journal of investigative dermatology}, year={1999}, volume={112 6}, pages={925-32} }