Downregulation of WIF-1 and Wnt5a in patients with colorectal carcinoma: clinical significance

Abstract

Activation of the wingless-type (Wnt) signaling pathway is common in various human cancers including colorectal cancer (CRC). Wnt inhibitory factor-1 (WIF-1) is a secreted antagonist that can bind Wnt ligands and therefore inhibits the Wnt signaling pathway. In this study, we aimed to analyze the expression of two members of Wnt signaling (WIF-1 and Wnt5a… (More)
DOI: 10.1007/s13277-014-2015-9

Topics

7 Figures and Tables