Downregulation of TLR‐7 receptor in hepatic and non‐hepatic patients with lichen planus

  title={Downregulation of TLR‐7 receptor in hepatic and non‐hepatic patients with lichen planus},
  author={A. E. El Tawdy and L. Rashed},
  journal={International Journal of Dermatology},
Background  Lichen planus (LP) is an inflammatory disease of the skin and oral mucosa. The association of LP and chronic hepatitis C virus (HCV) is well established, with variable prevalence rates among different populations. Toll‐like receptors (TLRs) are key regulators of both the innate response and the adaptive response. However, TLRs also interact with endogenous ligands released by necrotic cells, and this process can intensify autoimmune diseases such as rheumatoid arthritis and systemic… Expand
Potential pathogenic mechanisms involved in the association between lichen planus and hepatitis C virus infection.
Assessment of systemic inflammation with neutrophil-lymphocyte ratio in lichen planus


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