Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells.

@article{Kang2009DownregulationOP,
  title={Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells.},
  author={Gum-Yong Kang and E Lee and Jung-Hyun Kim and Jin Woo Jung and Jun Ren Lim and Sang Kyung Kim and Ssang-Goo Cho and Kwang Pyo Kim},
  journal={European journal of pharmacology},
  year={2009},
  volume={611 1-3},
  pages={
          17-21
        }
}
The molecular mechanisms underlying the kaempferol-induced cell death have not yet been fully explained. To investigate the role of kaempferol, widely distributed in foods, in tumor progression, human breast cancer cell line, MCF-7, was treated with kaempferol. Apoptosis was indicated by the accumulation of a sub-G1 population, as well as the appearance of 4'-6-diamidino-2-phenylindole (DAPI)-stained apoptotic nuclei in the MCF-7 cells after the administration of kaempferol. Western blot… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…