Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer.

@article{Gunduz2008DownregulationOI,
  title={Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer.},
  author={Mehmet Gunduz and Levent Bekir Beder and Esra Gunduz and Hitoshi Nagatsuka and Kunihiro Fukushima and Davut Pehlivan and Eren Cetin and Noboru Yamanaka and Kazunori Nishizaki and Kenji Shimizu and Noriyuki Nagai},
  journal={Cancer science},
  year={2008},
  volume={99 3},
  pages={531-8}
}
Although many clinical and pathological prognostic factors such as tumor stage and lymph-node involvement have been described, to date no reliable or clinically applicable marker or tumor aggressiveness has been identified for head and neck cancer. In an attempt to identify such a molecular prognostic marker, we analyzed the mRNA expression status of ING3 by quantitative reverse transcription-polymerase chain reaction. We also examined p53 mutation status and investigated its relationship with… CONTINUE READING

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