Downregulation of CK2 induces apoptosis in cancer cells – A potential approach to cancer therapy


We have previously documented that naked antisense CK2α ODN can potently induce apoptosis in cancer cells in culture and in mouse xenograft human prostate cancer. The effects of the antisense CK2α are related to downregulation of CK2α message and rapid loss of the CK2 from the nuclear compartment. Here we demonstrate that downregulation of CK2 elicited by… (More)
DOI: 10.1007/s11010-005-3077-1


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