Downregulation of ATP-binding cassette subfamily C member 4 increases sensitivity to neoadjuvant radiotherapy for locally advanced rectal carcinoma.

@article{Yu2013DownregulationOA,
  title={Downregulation of ATP-binding cassette subfamily C member 4 increases sensitivity to neoadjuvant radiotherapy for locally advanced rectal carcinoma.},
  author={Zhi-qi Yu and Chang P Zhang and Hao Wang and Xin-yuan Lao and Rui Tao Chai and Xian-hua Gao and Guangwen Cao and ChuanGang Fu},
  journal={Diseases of the colon and rectum},
  year={2013},
  volume={56 5},
  pages={
          600-8
        }
}
OBJECTIVE This study was designed to verify the effect of ATP-binding cassette subfamily C member 4 on radiosensitivity of locally advanced rectal carcinoma. SETTING The expression of ATP-binding cassette subfamily C member 4 protein in 121 pretreatment tissue samples from locally advanced rectal carcinoma patients was detected by immunohistochemistry. DESIGN Pathological response to radiotherapy was evaluated according to tumor regression grading by postoperative histological examinations… CONTINUE READING
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