Downregulated gelsolin expression in hyperplastic and neoplastic lesions of the prostate.

@article{Lee1999DownregulatedGE,
  title={Downregulated gelsolin expression in hyperplastic and neoplastic lesions of the prostate.},
  author={H K Lee and Deborah L. Driscoll and Harold L. Asch and Bonnie B. Asch and Paul J Zhang},
  journal={The Prostate},
  year={1999},
  volume={40 1},
  pages={14-9}
}
BACKGROUND Because of its role in cell motility and growth regulation, gelsolin, an actin-binding protein, has been considered a tumor suppressor and a potential prognostic marker in some neoplasias, such as breast and bladder cancer. Little is known about its immunoexpression in prostatic adenocarcinoma (PCA). METHODS Formalin-fixed, paraffin-embedded… CONTINUE READING