Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori–infected children

@article{Serrano2013DownregulatedTR,
  title={Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori–infected children},
  author={Carolina A. Serrano and Shelton W Wright and Diane Bimczok and Carrie L. Shaffer and Timothy L Cover and Alejandro Venegas and Manuela Gesell Salazar and Lesley E. Smythies and Paul R. Harris and Philip D. Coleridge Smith},
  journal={Mucosal Immunology},
  year={2013},
  volume={6},
  pages={950-959}
}
Helicobacter pylori induces less gastric inflammation in children than adults. Here we investigated whether this reduced inflammation involves dysregulated T helper type 17 (Th17) responses. H. pylori–infected children and adults in Santiago, Chile had similar levels of H. pylori colonization, proportions of bacteria containing cagA and s1/s2 vacA markers of virulence, and strain genotypes (predominantly hpEurope), but the children had significantly reduced levels of gastric inflammation and… CONTINUE READING
23 Extracted Citations
51 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 23 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 51 references

Similar Papers

Loading similar papers…