Downbeat nystagmus: aetiology and comorbidity in 117 patients.

  title={Downbeat nystagmus: aetiology and comorbidity in 117 patients.},
  author={Judith N Wagner and Mark Glaser and Tobias L. Brandt and Michael Strupp},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={79 6},
OBJECTIVES Downbeat nystagmus (DBN) is the most common form of acquired involuntary ocular oscillation overriding fixation. According to previous studies, the cause of DBN is unsolved in up to 44% of cases. We reviewed 117 patients to establish whether analysis of a large collective and improved diagnostic means would reduce the number of cases with "idiopathic DBN" and thus change the aetiological spectrum. METHODS The medical records of all patients diagnosed with DBN in our Neurological… CONTINUE READING


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