Down-regulation of the CD62L antigen as a possible mechanism for neutrophilia during inflammation.

  title={Down-regulation of the CD62L antigen as a possible mechanism for neutrophilia during inflammation.},
  author={Ori Rogowski and Yehuda Sasson and Micha Kassirer and David W Zeltser and Nitsan Maharshak and Nadir Arber and Peter J Halperin and J Serrov and Patric Sorkin and Amiram Eldor and Shlomo Berliner},
  journal={British journal of haematology},
  volume={101 4},
The expressions of both the CD11b/CD18 and CD62L (L-selectin) antigens as well as the absolute number of white blood cells in the peripheral circulating pool of blood in 116 patients with various inflammatory conditions were determined. A highly significant (P<0.0001) negative correlation (r = -0.57) was noted between the absolute number of peripheral blood polymorphonuclear leucocytes and the expression of the CD62L antigen on their surface. In view of the role of CD62L antigen in the rolling… CONTINUE READING

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