Down-regulation of miR-181b promotes apoptosis by targeting CYLD in thyroid papillary cancer.

  title={Down-regulation of miR-181b promotes apoptosis by targeting CYLD in thyroid papillary cancer.},
  author={Dengfeng Li and Wei Xia Jian and Chuankui Wei and Hongming Song and Yifan Gu and Yi Luo and Lin Fang},
  journal={International journal of clinical and experimental pathology},
  volume={7 11},
MicroRNAs (miRNAs) are a small class of non-coding RNAs that are widely deregulated in various cancers. They act as either oncogenes or tumor suppressor genes in human cancer. The purpose of this study was to examine the potential role of miR-181b in human thyroid papillary cancer. The expression levels of different miRNAs were measured by micro array analysis in 10 thyroid papillary cancer specimens and adjacent normal thyroid cancer tissues. MTT assays, colony formation assays, apoptosis… CONTINUE READING
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