Down-regulation of gut-enriched Kruppel-like factor expression in esophageal cancer.

  title={Down-regulation of gut-enriched Kruppel-like factor expression in esophageal cancer.},
  author={Nan Wang and Zhihua Liu and Fang Ding and Xiu-qin Wang and Chuan-nong Zhou and Min Wu},
  journal={World journal of gastroenterology},
  volume={8 6},
AIM Esophageal carcinoma is one of the most common malignant tumors in China. But the molecular mechanisms of esophageal carcinoma remains unclear. Gut-enriched Kruppel-like factor (GKLF) is a newly identified transcription factor which is expressed abandantly in the epithelial cells of the gastrointestinal tract and deregulation of GKLF was linked to several types of cancer. It is of interest to study the expression and role of GKLF in esophageal carcinoma. METHODS Semi-quantitative RT-PCR… CONTINUE READING


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