Down-regulation of fatty acid synthase increases the resistance of Saccharomyces cerevisiae cells to H2O2.

@article{Matias2007DownregulationOF,
  title={Down-regulation of fatty acid synthase increases the resistance of Saccharomyces cerevisiae cells to H2O2.},
  author={Ana C Matias and Nuno Pedroso and Nuno Teodoro and H Susana Marinho and Fernando Antunes and Jose Nogueira and Enrique Montero Herrero and Luisa Cyrne},
  journal={Free radical biology & medicine},
  year={2007},
  volume={43 10},
  pages={1458-65}
}
Changes in plasma membrane permeability caused by H2O2 were recently found to be involved in the adaptation to H2O2, but the mechanism responsible for this change remains largely unknown. Here this mechanism was addressed and two lines of evidence showed for the first time that fatty acid synthase (Fas) plays a key role during the cellular response of… CONTINUE READING