Down-regulation of MARCKS-related protein (MRP) in macrophages infected with Leishmania.

Abstract

Leishmania, a protozoan parasite of macrophages, has been shown to interfere with host cell signal transduction pathways including protein kinase C (PKC)-dependent signaling. Myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein (MRP, MacMARCKS) are PKC substrates in diverse cell types. MARCKS and MRP are thought to regulate the… (More)

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Cite this paper

@article{Corradin1999DownregulationOM, title={Down-regulation of MARCKS-related protein (MRP) in macrophages infected with Leishmania.}, author={Sally Corradin and Jacques Mau{\"e}l and Adriana Ransijn and C St{\"u}rzinger and Guy Vergeres}, journal={The Journal of biological chemistry}, year={1999}, volume={274 24}, pages={16782-7} }