Down-regulation in the Expression of the Rat-liver Serine Dehydratase during Chronic Metabolic Acidosis

Abstract

Blood pH controls the activity of important regulatory enzymes in the metabolism. Serine dehydratase (SerDH) transforms L-serine into pyruvate and ammonium and is involved in the regulation of gluconeogenesis from serine in rat liver. In this work, we investigate the effect of chronic metabolic acidosis on the kinetics, specific protein level, tissue… (More)

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@inproceedings{LpezFlores2006DownregulationIT, title={Down-regulation in the Expression of the Rat-liver Serine Dehydratase during Chronic Metabolic Acidosis}, author={Inmaculada L{\'o}pez-Flores and Juan Perag{\'o}n and Raquel Valderrama and Francisco J. Esteban and Francisco Luque and M {\'A}ngeles Peinado and F Salinas Aranda and Jos{\'e} Antonio Lupi{\'a}{\~n}ez and Juan B Barroso}, year={2006} }