Down-regulation but not phosphorylation of stathmin is associated with induction of HL60 cell growth arrest and differentiation by physiological agents.

@article{Johnson1995DownregulationBN,
  title={Down-regulation but not phosphorylation of stathmin is associated with induction of HL60 cell growth arrest and differentiation by physiological agents.},
  author={W Eustace Johnson and Natasha A Jones and David C. Rowlands and Alexia Williams and Steven S Guest and Geoffrey Brown},
  journal={FEBS letters},
  year={1995},
  volume={364 3},
  pages={309-13}
}
Stathmin is a cytosolic phosphoprotein that has an important but, as yet, undefined role in cell proliferation and differentiation. Induction of growth arrest and differentiation of HL60 cells to monocytes by phorbol 12-myristate 13-acetate is associated with rapid phosphorylation of the protein. Stathmin phosphorylation was not seen when HL60 cells were induced to differentiate to monocytes, by 1 alpha, 25-dihydroxyvitamin D3, and to neutrophils, by all-trans retinoic acid and granulocyte… CONTINUE READING

From This Paper

Topics from this paper.