Down's syndrome

  title={Down's syndrome},
  author={N. Roizen and D. Patterson},
  journal={The Lancet},
  • N. Roizen, D. Patterson
  • Published 2003
  • Medicine
  • The Lancet
  • The sequencing of chromosome 21 and the use of models of Down's syndrome in mice have allowed us to relate genes and sets of genes to the neuropathogenesis of this syndrome, and to better understand its phenotype. Research in prenatal screening and diagnosis aims to find methods to identify fetuses with Down's syndrome, and reduce or eliminate the need for amniocentesis. Other areas of active research and clinical interest include the association of Down's syndrome with coeliac disease and… CONTINUE READING
    812 Citations

    Paper Mentions

    Interventional Clinical Trial
    The purpose of this research study is to learn if the medication Memantine Hydrochloride (the study medication) can help adolescents and young adults with Down syndrome. Dr. Alberto… Expand
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    Down syndrome: advances in molecular biology and the neurosciences.
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    Prevalence of coeliac disease in Down's syndrome
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