Down's syndrome and Alzheimer's disease: towards secondary prevention

@article{Ness2012DownsSA,
  title={Down's syndrome and Alzheimer's disease: towards secondary prevention},
  author={Seth Ness and Michael S. Rafii and Paul S. Aisen and Michael Krams and W. Silverman and Husseini K. Manji},
  journal={Nature Reviews Drug Discovery},
  year={2012},
  volume={11},
  pages={655-656}
}
A public–private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common pathogenic role of amyloid precursor protein in the two conditions. 
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