Doubts about Preimplantation Genetic Screening for Aneuploidies: Will Liquid Biopsy Solve the Problem?

@inproceedings{Tesak2018DoubtsAP,
  title={Doubts about Preimplantation Genetic Screening for Aneuploidies: Will Liquid Biopsy Solve the Problem?},
  author={J. Tesař{\'i}k and Raquel Mendoza-Tesarik and C. Mendoza},
  year={2018}
}
There is growing concern about the current state of preimplantation genetic screening (PGS) for the detection of aneuploidies [1-3]. The opinions about the current place of PGS in this indication vary from the postulation of less rigid scoring systems for the evaluation of the risk associated with the transfer of embryos diagnosed with different types of aneuploidy [1] to a radical recommendation to discontinue the use of this technique until sufficient knowledge on genetic mosaicism in… CONTINUE READING

References

SHOWING 1-7 OF 7 REFERENCES
Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization
  • J. Xu, R. Fang, +14 authors S. Lu
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2016
  • 81
  • PDF
Liquid biopsies come of age: towards implementation of circulating tumour DNA
  • 792
  • PDF
Origins of mosaicism and criteria for the transfer of mosaic embryos.
  • S. Munné
  • Medicine, Biology
  • Reproductive biomedicine online
  • 2018
  • 7
Scoring of mosaic embryos after preimplantation genetic testing: a rollercoaster ride between fear, hope and embryo wastage.
  • 5