Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes.

@article{Shahinian1995DoublylipidmodifiedPS,
  title={Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes.},
  author={Serge Shahinian and John R Silvius},
  journal={Biochemistry},
  year={1995},
  volume={34 11},
  pages={3813-22}
}
To understand better the potential functional importance of the dual-lipid modifications found in a number of intracellular proteins of eukaryotes, we have examined how "tenaciously" various doubly-lipid-modified peptides, with sequences and lipid modifications reflecting those found in intracellular proteins, are anchored to lipid bilayer membranes. Fluorescent-labeled peptides bearing dual-lipid modifications were incorporated into large unilamellar egg phosphatidylcholine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

Similar Papers

Loading similar papers…