Doublet frequencies in the DNA of genetic code limit organisms


Unrelated organisms with DNA of extreme G + C content (25% or 70%) are found to share very specific patterns of nearest neighbour base doublet frequency in their DNAs. This is shown to be a result of restrictions on the extremity of amino acid composition in their proteins, combined with a maximisation of the use of one type of base pair in redundant codon… (More)
DOI: 10.1007/BF01654097


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