Double-wavelength technique for surface plasmon resonance measurements: basic concept and applications for single sensors and two-dimensional sensor arrays.

Abstract

A new technique for on-line monitoring of analyte binding to sensor surfaces by surface plasmon resonance (SPR) detection is described. It is based on differential measurements using two wavelengths provided by two diode lasers. The technique is as simple and robust as the conventional SPR detection measuring the reflected radiation at fixed incidence angle… (More)

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@article{Zybin2005DoublewavelengthTF, title={Double-wavelength technique for surface plasmon resonance measurements: basic concept and applications for single sensors and two-dimensional sensor arrays.}, author={Alexander Zybin and Christian Grunwald and Vladimir M Mirsky and Juergen Kuhlmann and Otto S. Wolfbeis and Kay Niemax}, journal={Analytical chemistry}, year={2005}, volume={77 8}, pages={2393-9} }