Double-wave-vector diffusion-weighted imaging reveals microscopic diffusion anisotropy in the living human brain.

@article{Lawrenz2013DoublewavevectorDI,
  title={Double-wave-vector diffusion-weighted imaging reveals microscopic diffusion anisotropy in the living human brain.},
  author={Marco Lawrenz and J{\"u}rgen Finsterbusch},
  journal={Magnetic resonance in medicine},
  year={2013},
  volume={69 4},
  pages={1072-82}
}
Diffusion-tensor imaging is widely used to characterize diffusion in biological tissue, however, the derived anisotropy information, e.g., the fractional anisotropy, is ambiguous. For instance, low values of the diffusion anisotropy in brain white matter voxels may reflect a reduced axon density, i.e., a loss of fibers, or a lower fiber coherence within the voxel, e.g., more crossing fibers. This ambiguity can be avoided with experiments involving two diffusion-weighting periods applied… CONTINUE READING

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