Double stranded aptamer-anchored reduced graphene oxide as target-specific nano detector.

@article{Kim2014DoubleSA,
  title={Double stranded aptamer-anchored reduced graphene oxide as target-specific nano detector.},
  author={Mi-Gyeong Kim and Yuna Shon and Jaiwoo Lee and Youngro Byun and Byeong-Sun Choi and Young Bong Kim and Young-kyoon Oh},
  journal={Biomaterials},
  year={2014},
  volume={35 9},
  pages={
          2999-3004
        }
}
Here, we report a double-stranded, dual-anchored, fluorescent aptamer on reduced graphene oxide (rGO) for the sensitive, selective, and speedy detection of a target protein in biological samples. This nano detector is composed of a target protein-specific fluorescent aptamer with BHQ1 as one anchoring moiety that forms double-stranded sequences with a complementary oligonucleotide sequence with BHQ1 as the other anchoring moiety, anchored to rGO nanosheets. The double-stranded and dual-anchored… CONTINUE READING
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