Double step paraneoplastic brainstem encephalitis: a clinicopathological study
@article{Vigliani2009DoubleSP, title={Double step paraneoplastic brainstem encephalitis: a clinicopathological study}, author={Maria Claudia Vigliani and Domenico Novero and Paolo Cerrato and Dino Daniele and Stefania Greco Crasto and Maurizio Berardino and Roberto Mutani}, journal={Journal of Neurology, Neurosurgery, and Psychiatry}, year={2009}, volume={80}, pages={693 - 695} }
A case of brainstem encephalitis in a man positive for both anti-Hu and anti-Ri antibodies is reported. This case had an unusual double step evolution and progressive involvement of different CNS subdivisions at MRI. Brainstem encephalitis developed abruptly, mimicking a posterior vascular deficit with vertigo and dizziness. These symptoms transiently remitted completely after a few days to relapse acutely 1 month later with sudden loss of consciousness, followed by confusion, disorientation…
12 Citations
Biphasic paraneoplastic brainstem encephalitis associated with anti-Ri antibody
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Keegan and colleagues beautifully and succinctly described 'CLIPPERS' (Pittock et al., 2010)—Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids—as a distinct form of idiopathic brainstem encephalitis centred on the pons.
The other BSE.
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There followed a long period of uncertainty as to whether Fisher and Bickerstaff syndromes were one and the same, and of central or peripheral origin; only in the last few years has immunological characterization begun to resolve these matters.
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The neuropathological findings and pathophysiology of paraneoplastic CNS disorders with reference to antigen-specific serology and neurological and oncological contexts are described.
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- 2011
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Various clinical features of patients with anti-Hu associated paraneoplastic neurological syndromes
- Medicine, PsychologyMedicine
- 2018
EEG may be more sensitive than MRI for early diagnosis of PNS and long-term follow-up for patients with CT-negative anti-Hu associated PNS is necessary.
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Jaw dystonia and laryngospasm are common accompaniments of ANNA-2 autoimmunity and are associated with significant morbidity, and it is proposed that selective damage to antigen-containing inhibitory fibers innervating bulbar motor nuclei by CD8(+) T lymphocytes is the proximal cause of this syndrome.
Symmetrical Curvilinear Cytotoxic Edema Along the Surface of the Brain Stem: A Probable New Magnetic Resonance Imaging Finding of Leptomeningeal Carcinomatosis
- MedicineMedicine
- 2015
This unique imaging finding of symmetric curvilinear nonenhancing cytotoxic edema along the brainstem is extremely rare and represents a new presentation of leptomeningeal carcinomatosis.
Brain immunohistopathological study in a patient with anti‐NMDAR encephalitis
- Medicine, BiologyEuropean journal of neurology
- 2011
An immunohistopathological study of the inflammatory reaction in a brain biopsy performed before immunomodulatory treatments in a patient with anti‐NMDA receptor encephalitis is performed.
Objawy oczne w zespołach paranowotworowych
- 2009
Uszkodzenie ukladu wzrokowego, bedące odleglym nastepstwem
choroby nowotworowej, zwykle objawia sie nieprawidlowymi ruchami
galek ocznych lub oslabieniem ostrości wzroku i ubytkami
w polu widzenia.…
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