Double resection for patients with pancreatic cancer and a second primary renal cell cancer.

Abstract

BACKGROUND Reports of synchronous or metachronous double kidney-pancreas cancers are very rare. METHODS We present 2 patients with renal cell carcinoma and synchronous (1 patient) or metachronous (1 patient) primary pancreatic ductal adenocarcinoma. The patients underwent resection for both cancer types with a worthwhile outcome. RESULTS The appearance of different primaries in an individual may indicate a genetic predisposition to different neoplasms. The study of double primary cancers is important because it might provide understanding of a shared genetic basis of different solid tumors. CONCLUSIONS The association between these two cancers demands more detailed epidemiological and molecular investigation. From a clinical viewpoint a resectional policy is recommended.

Cite this paper

@article{Alexakis2003DoubleRF, title={Double resection for patients with pancreatic cancer and a second primary renal cell cancer.}, author={Nicholas Alexakis and Lorraine Bosonnet and Saxon J. Connor and Ian H Ellis and R Sutton and Fiona Campbell and Mark L Hughes and Conall J Garvey and J . P . Neoptolemos}, journal={Digestive surgery}, year={2003}, volume={20 5}, pages={428-32} }