Double gaps along Shaker S4 demonstrate omega currents at three different closed states.

@article{ElDin2010DoubleGA,
  title={Double gaps along Shaker S4 demonstrate omega currents at three different closed states.},
  author={Tamer M Gamal El-Din and Hansjakob Heldstab and Claudia Lehmann and Nikolaus G. Greeff},
  journal={Channels},
  year={2010},
  volume={4 2},
  pages={
          93-100
        }
}
  • Tamer M Gamal El-Din, Hansjakob Heldstab, +1 author Nikolaus G. Greeff
  • Published in Channels 2010
  • Biology, Medicine
  • The aim of the present study was to investigate in detail how the voltage sensor in the Shaker potassium channel moves during the gating process. After the publication of the open channel structure from the crystallized K(V)AP channel in 2003, an alternative so-called "paddle" model was put forward in contrast to the existing helical screw model. The voltage sensor S4 contains 4 arginine residues relevant for gating, R1(362), R2(365), R3(368) and R4(371), each separated by 2 neutral residues… CONTINUE READING

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