Double-dose, new-generation proton pump inhibitors do not improve Helicobacter pylori eradication rate.

@article{Choi2007DoubledoseNP,
  title={Double-dose, new-generation proton pump inhibitors do not improve Helicobacter pylori eradication rate.},
  author={Hyo Sun Choi and Dong Il Park and Sang Jun Hwang and Jung Sik Park and Hong Joo Kim and Yong Kyun Cho and Chong Il Sohn and Woo Kyu Jeon and Byung Ik Kim},
  journal={Helicobacter},
  year={2007},
  volume={12 6},
  pages={638-42}
}
BACKGROUND Up to present, omeprazole plus two antibiotics are used for Helicobacter pylori eradication therapy . Few studies have compared double-dose new-generation, proton pump inhibitors (PPI) with omeprazole. Therefore, we conducted a randomized, prospective study to evaluate differences in H. pylori eradication rates by PPI type. MATERIAL AND METHODS Between January 2006 and December 2006, 576 consecutive patients with proven H. pylori infection were enrolled prospectively. Four… CONTINUE READING

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